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Professor Stephen Fletcher

Associate Professor of Organic Chemistry

Tutorial Fellow in Organic Chemistry


Welcome to my College web page, I'm relatively new here, having started as a Tutorial Fellow in 2015. I am originally from, and studied in, Canada. I was a postdoctoral researcher in the Netherlands and Manchester before coming to Oxford in 2009. My subject is organic chemistry. I give tutorials at Keble on all aspects of organic chemistry, as well as undergraduate and graduate lectures on organic chemistry in the Department.

Research Interests

I'm broadly interested in seeing what can be accomplished using organic chemistry! My research groups specialty is synthesising new molecular materials in new ways, and to use organic molecules to help understand chemical, physical and biological phenomena.

We are particularly interested in i) developing new catalytic asymmetric carbon-carbon bond forming methods using readily available starting materials, and ii)  in developing self-replicating systems and autocatalytic reaction networks that may be relevant to the origins of life on Earth.

A few selected papers:

Rhodium-catalysed asymmetric allylic arylation of racemic halides with arylboronic acids. M. Sidera and S. P. Fletcher. Nature Chem. 2015, 7, 935-939.

Non-stabilized nucleophiles in Cu-catalysed dynamic kinetic asymmetric allylic alkylation. H. You, E. Rideau, M. Sidera and S. P. Fletcher. Nature 2015, 517, 351–355.

Physical autocatalysis driven by a bond-forming thiol-ene reaction. A. J. Bissette, B. Odell and S. P. Fletcher. Nature Comm. 2014, 5, 4607.

Conversion of light into macroscopic helical motion. S. Iamsaard, S. J. Aβhoff, B. Matt, T. Kudernac, J. J. L. M. Cornelissen, S. P. Fletcher and N. Katsonis. Nature Chem. 2014, 6, 229-235.

Synthetic control of retinal photochemistry and photophysics in solution. G. Bassolino, T. Sovdat, M. Liebel, C. Schnedermann, B. Odell, T. D. W. Claridge, P. Kukura and S. P. Fletcher. J. Am. Chem. Soc. 2014, 136, 2650-2658.

Mechanisms of autocatalysis.  A. J. Bissette and S. P. Fletcher. Angew. Chem. Int. Ed. 2013, 52, 12800–12826.

Catalytic asymmetric carbon-carbon bond formation using alkenes as alkylmetal equivalents.  R. M. Maksymowicz, P. M. C. Roth and S. P. Fletcher. Nature Chem. 2012, 4​, 649–654.

For more detailed information, please see my Departmental and Group websites

College Contact Details

Professor Stephen Fletcher
Keble College
Telephone: 01865 272727
Fax: 01865 272705

Faculty/Dept. Information

University of Oxford
Chemistry Research Laboratory
12 Mansfield Road
Oxford OX1 3TA