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Dr Ulrike Gruneberg

Fellow and Tutor in Medicine and Biomedical Sciences

MRC Senior Research Fellow, Associate Professor in Experimental Pathology

Welcome

Welcome to my Keble web page. I am a tutorial fellow in medicine with a focus on Cell Biology and Immunology. I am particularly interested in the cellular origins of cancer and the role of chromosome segregation errors in tumorigenesis. My lab’s research focuses on understanding the mechanics and regulation of cell division and chromosome segregation in human cells. Aneuploidy, the condition where chromosomes are either lost or gained, is a consequence of faulty chromosome segregation and is considered both a hallmark and a driving force for tumorigenesis. A better appreciation of the processes ensuring accurate chromosome segregation may therefore lead to novel therapeutic approaches for cancer. Many molecular players contributing to the formation of the mitotic spindle and kinetochores have recently been identified, however, the precise biochemical activities of these components and how they are dynamically regulated throughout mitosis is often not understood. Our goal is to integrate the identification of components contributing to mitotic progression with the characterization of their biological function.

Recent Publications

College Contact Details

Dr Ulrike Gruneberg
Keble College
Oxford
OX1 3PG
UK
Telephone: 01865 285662
Fax: 01865 272705
Email:

Faculty/Dept. Information

Sir William Dunn School of Pathology
South Parks Road
OX1 3RE
Tel.: 01865 285662

Website:
http://www.path.ox.ac.uk/content/ulrike-gruneberg